Since its inception in the early 1990s, OCT has evolved beyond ophthalmologic imaging of the retina to recent advances in the dual-modality diagnosis of coronary artery disease using fiber optic probes. OCT catheters designed for semi-invasive in vivo intervention require small form factor optical fibers, dispersion control, bend insensitivity, and high proof strength for superior mechanical reliability. Our OCT offerings also include pure silica core waveguides supporting sterilization by radiation as well as thin biocompatible coatings such as polyimide when form factor and reliability are paramount.